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First, a patient would likely need castration surgery and high doses of exogenous hormones because high levels of male sex hormones, called androgens, could threaten pregnancy. The surgery is still very experimental, even among natal women. With each patient, the subsequent conversations were an exercise in tamping down expectations. Even if the hormonal and anatomical challenges are overcome, for someone who was born producing sperm instead of eggs there would be one more hurdle. Then he moved on to sheep and baboons. To support a fetus through pregnancy a transgender recipient would also need the right hormonal milieu and the vasculature to feed the uterus, along with a vagina. Such a future is hard to imagine, at least in the near term. The next natural step for those interested in assisting transgender or male patients, however, would likely be tackling this procedure among women with a rare condition called androgen insensitivity syndrome , he says. Additionally, it is unclear how demand for a uterus would be weighed by a hospital or an organization like the United Network for Organ Sharing. The resulting baby would have to be born through cesarean section—as a safety precaution to limit stress on the transplanted organ, and because the patient cannot feel labor contractions nerves are not transplanted with the uterus. Two years ago, in a medical first, he managed to help a human womb—transplant patient deliver her own baby boy. But a major catch is the medical risk they face. A Risky Prospect The trouble is that uterine transplants are extremely complex and resource-intensive, requiring dozens of health personnel and careful coordination.

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Description: For as long as we've been making babies, women have been exchanging ideas about how to have either a boy or a girl. This is because male sperm are not as strong as female sperm, and so the higher the Inside pregnancy: girl or boy?. With each patient, the subsequent conversations were an exercise in tamping down expectations. He wanted to give them a chance at birthing their own children, especially in countries like his native Sweden where surrogacy is illegal. Yet with six planned uterine transplant clinical trials among natal female patients across the U. Here is how it could work. More efforts are expected in the United States. Dina Fine Maron, formerly an associate editor at Scientific American , is now a wildlife trade investigative reporter at National Geographic. A standard hysterectomy takes between a half-hour and an hour, but preparing a uterus and its associated blood vessels for transplant would keep such patients under the knife for as long as 10 or 11 hours. But a major catch is the medical risk they face. Biological Connection Even if the hormonal and anatomical challenges are overcome, for someone who was born producing sperm instead of eggs there would be one more hurdle. Even if the hormonal and anatomical challenges are overcome, for someone who was born producing sperm instead of eggs there would be one more hurdle. If the patient does not have further complications, a year later a doctor may then implant an embryo created via in vitro fertilization. Such potential donors may seem ideal because they are not pursuing a hysterectomy due to disease. Additionally, it is unclear how demand for a uterus would be weighed by a hospital or an organization like the United Network for Organ Sharing. To support a fetus through pregnancy a transgender recipient would also need the right hormonal milieu and the vasculature to feed the uterus, along with a vagina.
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